Posaconazole (200 mg 3 times daily) can be used with cure rate of 80%.

In fluconazole resistant cases: Itraconazole (200 mg twice daily) can be used with cure rate between 64 - 80%.

Continuous prophylactic fluconazole use is more effective than intermittent use in response to relapses.

In pediatric patients: use itraconazole in a dose of 2.5 mg/kg/day.

Most immunocompromised patients respond initially to topical agents using the same regimen above but relapses occur rapidly unless fluconazole (400 mg [6 mg/kg} daily)is not used.

Medical treatment of oropharyngeal candidiais in immunocompromised patients:.

For refractory disease, consider the alternative regimen. Fluconazole is recommended in moderate-to-severe disease, and topical therapy with Clotrimazole or Nystatin is recommended for mild disease. Note: Treat uncomplicated disease for 7–14 days.Alternative regimen: Itraconazole solution 200 mg PO q24h OR Posaconazole 400 mg PO q24h OR Voriconazole 200 mg PO q24h OR Amphotericin B oral suspension PO q24h OR ( Anidulafungin 200 mg IV once THEN Anidulafungin 100 mg IV q24h) OR ( Caspofungin 70 mg IV once THEN Caspofungin 50 mg IV q24h) OR Micafungin 100 mg IV q24h OR Amphotericin B 0.3 mg/kg IV q24h.Preferred regimen: Clotrimazole troches 10 mg TOP q4-5h OR Nystatin suspension or pastilles TOP q6h OR Fluconazole 100–200 mg PO q24h.Systemic antifungal medication such as fluconazole or itraconazole may be necessary for oropharyngeal infections that do not respond to these treatments. Oral candidiasis usually responds to topical treatments such as clotrimazole troches and nystatin suspension ( nystatin - swish and swallow). Patients who are immunocompromised, either with HIV/ AIDS or as a result of chemotherapy, may require systemic treatment with oral or intravenous administered antifungals.

Oral candidiasis can be treated with topical anti-fungal drugs, such as nystatin (mycostatin), miconazole or amphotericin B. Patients who are immunocompromised, either with HIV/ AIDS or as a result of chemotherapy, may require systemic treatment with oral or intravenous administered antifungals.Īny underlying cause, such as poor glucose control in diabetics, should be addressed. Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH Overview Risk calculators and risk factors for Oral candidiasis medical therapyĮditor-In-Chief: C. Oral candidiasis medical therapy in the newsīlogs on Oral candidiasis medical therapyĭirections to Hospitals Treating Oral candidiasis Oral candidiasis medical therapy On the WebĪmerican Roentgen Ray Society Images of Oral candidiasis medical therapyĪll Images X-rays Echo & Ultrasound CT Images MRI

Natural History, Complications and Prognosis For a full list, see the leaflet inside your medicine packet.Differentiating Oral candidiasis from other Diseases These are not all the side effects of nystatin. These can be signs of a serious allergic reaction and may need immediate treatment in hospital. You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face).you suddenly become very confused, drowsy or dizzy.your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet).your throat feels tight or you're struggling to swallow.you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air).your lips, mouth, throat or tongue suddenly become swollen.

Nystatin swish swallow